Pharmacoinformatics and molecular dynamic simulation studies to identify potential small-molecule inhibitors of WNK-SPAK/OSR1 signaling that mimic the RFQV motifs of WNK kinases-Reference-Cited by-同舟云学术

Pharmacoinformatics and molecular dynamic simulation studies to identify potential small-molecule inhibitors of WNK-SPAK/OSR1 signaling that mimic the RFQV motifs of WNK kinases

Published:2020-04 Issue:4 Volume:13 Page:5107-5117
ISSN:1878-5352
Container-title:Arabian Journal of Chemistry
language:en
Short-container-title:Arabian Journal of Chemistry

Author:

Alamri Mubarak A.^ORCID

Funder

Prince Sattam Bin Abdulaziz University, Saudi Arabia

Publisher

Elsevier BV

Subject

General Chemical Engineering,General Chemistry

Reference45 articles.

1. Sequence specific assignment and determination of OSR1 C-terminal domain structure by NMR;AlAmri;Biochem. Biophys. Res. Commun.,2019

2. Rafoxanide and closantel inhibit SPAK and OSR1 kinases by binding to a highly conserved allosteric site on their C-terminal domains;AlAmri;ChemMedChem,2017

3. The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters;Alessi;Sci. Signal.,2014

4. Structure and ligand based drug design strategies in the development of novel 5-LOX inhibitors;Aparoy;Curr. Med. Chem.,2012

5. Receptor-based virtual screening protocol for drug discovery;Cerqueira;Arch. Biochem. Biophys.,2015

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular docking and molecular dynamics simulation studies of the interaction of anti-oral cancer plant Curcuma longa derived-compounds with human epidermal growth factor receptor 2;Journal of Proteins and Proteomics;2024-07-16

2. From desert flora to cancer therapy: systematic exploration of multi-pathway mechanisms using network pharmacology and molecular modeling approaches;Frontiers in Pharmacology;2024-04-11

3. Cracking a cancer code DNA methylation in epigenetic modification: an in-silico approach on efficacy assessment of Sri Lanka-oriented nutraceuticals;Journal of Biomolecular Structure and Dynamics;2024-02-29

4. Identification of novel inhibitors against VP40 protein of Marburg virus by integrating molecular modeling and dynamics approaches;Journal of Biomolecular Structure and Dynamics;2024-01-04

5. Synthesis, in silico and in vitro studies of novel quinazolinone derivatives as potential SARS-CoV-2 3CLpro inhibitors;Arabian Journal of Chemistry;2024-01