A novel inhibitor, 2-cyano-3-(1-phenyl-3-(thiophen-2-yl)-pyrazol-4-yl)acrylamide linked to sulphamethoxazole, blocks anti-apoptotic proteins via molecular docking and strongly induced apoptosis of HCT116 cell line by different molecular tools
Author:
Publisher
Elsevier BV
Subject
General Chemical Engineering,General Chemistry
Reference52 articles.
1. Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII;Alafeefy;Bioorg. Med. Chem.,2013
2. p53-Mdm2–the affair that never ends;Alarcon-Vargas;Carcinogenesis,2002
3. A novel adamantane thiadiazole derivative induces mitochondria-mediated apoptosis in lung carcinoma cell line;Ali;Bioorg. Med. Chem.,2017
4. Antidiabetic activity of aqueous extract of sigesbeckia orientalis (St. paul’s wort) in alloxan-induced diabetes model. Brazilian;Asif;J. Pharm. Sci.,2019
5. A concept of mould spoilage prevention and acrylamide reduction in wheat bread: Application of lactobacilli in combination with a cranberry coating;Bartkiene;Food Control,2018
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1. Novel Bis(2‐cyanoacrylamide) Linked to Sulphamethoxazole: Synthesis, DNA Interaction, Anticancer, ADMET, Molecular Docking, and DFT Studies;Chemistry & Biodiversity;2024-03-08
2. Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma;Scientific Reports;2023-12-15
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4. Recent Advances in Biological Active Sulfonamide-based Hybrid Compounds Part C: Multicomponent Sulfonamide Hybrids;Current Medicinal Chemistry;2022-11-28
5. Computational studies and sever apoptotic bioactivity of new heterocyclic cyanoacrylamide based p-fluorophenyl and p-phenolic compounds against liver carcinoma (Hepg2);Bioorganic Chemistry;2021-09
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