Alkaloid chemodiversity in Mandragora spp. is associated with loss-of-functionality of MoH6H, a hyoscyamine 6β-hydroxylase gene

Author:

Schlesinger Daniel,Davidovich Rikanati Rachel,Volis Sergei,Faigenboim Adi,Vendramin Vera,Cattonaro Federica,Hooper Matthew,Oren Elad,Taylor Mark,Sitrit Yaron,Inbar Moshe,Lewinsohn Efraim

Funder

European Union’s seventh framework program for research, technological development and demonstration

Publisher

Elsevier BV

Subject

Plant Science,Agronomy and Crop Science,Genetics,General Medicine

Reference36 articles.

1. Substances isolated from Mandragora species;Hanus;Phytochemistry,2005

2. An evaluation of the mechanism of scopolamine-induced impairment in two passive avoidance protocols;Elrod;Pharmacol. Biochem. Behav.,1988

3. Alkaloids;Dewick,2002

4. Molecular cloning of hyoscyamine 6β-hydroxylase, a 2-oxoglutarate-dependent dioxygenase, from cultured roots of Hyoscyamus niger;Matsuda;J. Biol. Chem.,1991

5. Hyoscyamine 6β-hydroxylase, a 2-oxoglutarate-dependent dioxygenase, in alkaloid-producing root cultures;Hashimoto;Plant Physiol.,1986

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