High-performance liquid chromatographic determination of N-[2- (hydroxyethyl)-N-(2-(7-guaninyl)ethyl)]methylamine, a reaction product between nitrogen mustard and DNA and its application to biological samples

Author:

Sperry Michelle L,Skanchy David,Marino Mark T

Publisher

Elsevier BV

Subject

General Chemistry

Reference10 articles.

1. B.A. Chabner, C.J. Allegro, G.A. Curt, P. Calabresi, in: A.G. Gilman, T.W. Rall, A.S. Nies, P. Taylor (Editors), Goodman and Gilman's The Pharmacologic Basis of Therapeutics, Pergamon Press, New York, 1995, Ch. 51, p. 1233.

2. Alkylation of DNA by the Nitrogen Mustard Bis-(2-chloroethyl)methylamine

3. Starks Associates, Buffalo, NY, US Army Medical Research and Material Command Contract No. DAND17-93-C-3003.

4. Separation of 7-methyl- and 7-(2-hydroxyethyl)-guanine adducts in human DNA samples using a combination of TLC and HPLC

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