Enantiomeric separation of metoprolol and α-hydroxymetoprolol by liquid chromatography and fluorescence detection using a chiral stationary phase
Author:
Publisher
Elsevier BV
Subject
General Chemistry
Reference24 articles.
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2. Chemical aspects of metoprolol metabolism. Asymmetric synthesis and absolute configuration of the 3-[4-(1-hydroxy-2-methoxyethyl)phenoxy]-1-(isopropylamino)-2-propanols, the diastereomeric benzylic hydroxylation metabolites
3. Enantioselective and diastereoselective aspects of the oxidative metabolism of metoprolol
4. Resolution of the enantiomers of propranolol and other beta-adrenergic antagonists by high-performance liquid chromatography
5. Determination of (R)- and (S)-alprenolol and (R)- and (S)-metoprolol as their diastereomeric derivatives in human plasma by reversed-phase liquid chromatography
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