Mechanism of paracetamol toxicity

Author:

Hinson J.A.,Roberts D.W.,Benson R.W.,Dalhoff K.,Loft S.,Poulsen H.E.

Publisher

Elsevier BV

Subject

General Medicine

Reference8 articles.

1. Acetaminophen-induced hepatic injury: Protective role of glutathione in man and rationale for therapy;Mitchell;Clin Pharmacol Ther,1974

2. Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose;Smilkstein;N Engl J Med,1988

3. N-acetyl-p-benzoquinone imine: a cytochrome P-450 mediated oxidation product of acetaminophen;Dahlin;Proc Natl Acad Sci USA,1984

4. A sensitive immunochemical assay for acetaminophen-protein adducts;Roberts;J Pharmacol Exp Ther,1987

5. Epitope characterization of acetaminophen bound to protein and nonprotein sulfhydryl groups by an enzyme linked immunosorbent assay;Potter;J Pharmacol Exp Ther,1988

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