An innovative platform to improve asymmetric bispecific antibody assembly, purity, and expression level in stable pool and cell line development-Reference-Cited by-同舟云学术

An innovative platform to improve asymmetric bispecific antibody assembly, purity, and expression level in stable pool and cell line development

Published:2022-12 Issue: Volume:188 Page:108683
ISSN:1369-703X
Container-title:Biochemical Engineering Journal
language:en
Short-container-title:Biochemical Engineering Journal

Author:

Wang Yanling^ORCID,Qiu Haoran^ORCID,Minshull Jeremy,Tam Wilburt,Hu Xichan,Mieczkowski Carl,Zheng Weibin^ORCID,Chu Chun,Liu Wenqiang,Boldog Ferenc,Gustafsson Claes^ORCID,Gries Jean-Michel^ORCID,Xu Wenfeng

Publisher

Elsevier BV

Subject

Biomedical Engineering,Environmental Engineering,Bioengineering,Biotechnology

Reference22 articles.

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3. Progress in overcoming the chain association issue in bispecific heterodimeric IgG antibodies;Klein;MAbs,2012

4. J.B.B. Ridgway, L.G. Presta, P. Carter, “Knobs-into-holes” engineering of antibody C H 3 domains for heavy chain heterodimerization, 1996. 〈https://academic.oup.com/peds/article/9/7/617/1527831〉.

5. Expression liabilities in a four-chain bispecific molecule;Guo;Biotechnol. Bioeng.,2021

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3. Mitigating the aggregation challenge in immunocytokine production: Strategies during cell line development and purification optimization;Biochemical Engineering Journal;2024-03

4. Facilitating high throughput bispecific antibody production and potential applications within biopharmaceutical discovery workflows;mAbs;2024-02-21

5. Droplet digital PCR: A comprehensive tool for genetic analysis and prediction of bispecific antibody assembly during cell line development;New Biotechnology;2023-12