Improving the Cβ stereoselectivity of L-threonine aldolase for the preparation of L-threo-3,4-dihydroxyphenylserine, a powerful anti-Parkinson's disease drug-Reference-Cited by-同舟云学术

Improving the Cβ stereoselectivity of L-threonine aldolase for the preparation of L-threo-3,4-dihydroxyphenylserine, a powerful anti-Parkinson's disease drug

Published:2023-02 Issue: Volume:191 Page:108766
ISSN:1369-703X
Container-title:Biochemical Engineering Journal
language:en
Short-container-title:Biochemical Engineering Journal

Author:

Zha Renfen,Lei Bijing,Ma Jinsong,Zhang Zhi,Pan Yinping,Wang Bochu,Qi Na

Publisher

Elsevier BV

Subject

Biomedical Engineering,Environmental Engineering,Bioengineering,Biotechnology

Reference18 articles.

1. An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis;Scott;Nat. Commun.,2017

2. Scalable and selective β-hydroxy-α-amino acid synthesis catalyzed by promiscuous L-threonine transaldolase ObiH;Doyon;Chembiochem,2022

3. Threonine aldolases: perspectives in engineering and screening the enzymes with enhanced substrate and stereo specificities;Fesko;Appl. Microbiol. Biotechnol.,2016

4. PLP-dependent enzymes as important biocatalysts for the pharmaceutical, chemical and food industries: a structural and mechanistic perspective;Rocha;Catal. Sci. Technol.,2019

5. Directed evolution of L-threonine aldolase for the diastereoselective synthesis of β-hydroxy-α-amino acids;Zheng;ACS Catal.,2021

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