Efficient synthesis of l-tert-leucine through reductive amination using leucine dehydrogenase and formate dehydrogenase coexpressed in recombinant E. coli

Author:

Liu Weiming,Ma Hongmin,Luo Jixing,Shen Wenhe,Xu Xian,Li Shuang,Hu Yi,Huang He

Funder

National Key Research and Development Program of China

China National Funds for Distinguished Young Scientists

National High-tech Research and Development Program

Publisher

Elsevier BV

Subject

Biomedical Engineering,Environmental Engineering,Bioengineering,Biotechnology

Reference36 articles.

1. Novel biosynthetic approaches to the production of unnatural amino acids using transaminases;Taylor;Trends Biotechnol.,1998

2. Methods for the synthesis of unnatural amino acids;Ager;Curr. Opin. Drug Discovery Dev.,2001

3. Biocatalysis to amino acid-based chiral pharmaceuticals-examples and perspectives;Bommarius;J. Mol. Catal. B: Enzym.,1998

4. Synthesis and use of enantiomerically pure tert-leucine;Bommarius;Tetrahedron: Asymmetry,1995

5. Biocatalysis for pharmaceutical intermediates: the future is now;Pollard;Trends Biotechnol.,2007

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