NK1 (substance P) receptor antagonists – why are they not analgesic in humans?

Author:

Hill Ray

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference18 articles.

1. Discrepant results from preclinical and clinical studies on the potential of substance P–receptor antagonist compounds as analgesics;Boyce,2000

2. Discovery of the anti-depressant and anti-emetic efficacy of substance receptor (NK1) antagonists;Rupniak;Trends Pharmacol. Sci.,1999

3. The history of substance P.;Von Euler,1985

4. Neurotransmitter candidates of somatosensory primary afferent fibres;Salt;Neuroscience,1983

5. Cerebrospinal fluid neuropeptides and monoaminergic transmitters in patients with trigeminal neuralgia;Strittmatter;Headache,1997

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