FTY720: a novel transplantation drug that modulates lymphocyte traffic rather than activation

Author:

Brinkmann Volker,Pinschewer Daniel,Chiba Kenji,Feng Lilli

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference30 articles.

1. Design, synthesis, and structure–activity relationships of 2-substituted-2-amino-1,3–propanediols: discovery of a novel immunosuppressant, FTY720;Adachi;Bioorg. Med. Chem. Lett.,1995

2. Simple compounds, 2-alkyl-2-amino-1,3-propanediols have potent immunosuppressive activity;Fujita;Bioorg. Med. Chem. Lett,1995

3. Potent immunosuppressants, 2-alkyl-2-aminopropane-1,3-diols;Fujita;J. Med. Chem.,1996

4. 2-Substituted 2-aminoethanol: minimum essential structure for immunosuppressive activity of ISP-I (myriocin);Fujita;Bioorg. Med. Chem. Lett.,1995

5. FTY720, a novel immunosuppressant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with CsA in rats;Chiba;Transplant. Proc,1996

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