Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization-Reference-Cited by-同舟云学术

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Genotype-Fitness Maps of EGFR-Mutant Lung Adenocarcinoma Chart the Evolutionary Landscape of Resistance for Combination Therapy Optimization

Published:2020-01 Issue:1 Volume:10 Page:52-65.e7
ISSN:2405-4712
Container-title:Cell Systems
language:en
Short-container-title:Cell Systems

Author:

Bolan Patrick O.,Zviran Asaf,Brenan Lisa,Schiffman Joshua S.,Dusaj Neville,Goodale Amy,Piccioni Federica,Johannessen Cory M.,Landau Dan A.

Funder

National Institutes of Health

Stand Up To Cancer

Publisher

Elsevier BV

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

Reference66 articles.

1. Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors;Adalsteinsson;Nat. Commun.,2017

2. Tumour evolution: Clonal ancestry in lung cancer;Alderton;Nat. Rev. Cancer,2014

3. High-throughput Phenotyping of Lung Cancer Somatic Mutations;Berger;Cancer Cell,2016

4. Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers;Blakely;Nat. Genet.,2017

5. RAS–MAPK reactivation facilitates acquired resistance inFGFR1-amplified lung cancer and underlies a rationale for upfront FGFR–MEK blockade;Bockorny;Mol. Cancer Ther.,2018

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1. The evolutionary theory of cancer: challenges and potential solutions;Nature Reviews Cancer;2024-09-10

2. Association between methyltransferase-like 3 and non-small cell lung cancer: pathogenesis, therapeutic resistance, and clinical applications;Translational Lung Cancer Research;2024-05

3. Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants;Nature Communications;2024-03-28

4. Molecular mechanism of ion channel protein TMEM16A regulated by natural product of narirutin for lung cancer adjuvant treatment;International Journal of Biological Macromolecules;2022-12

5. The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC;Biomedicine & Pharmacotherapy;2022-12

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