Treatment of experimental status epilepticus with the GABA uptake inhibitor, tiagabine-Reference-Cited by-同舟云学术

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Treatment of experimental status epilepticus with the GABA uptake inhibitor, tiagabine

Published:1994-12 Issue:3 Volume:19 Page:237-244
ISSN:0920-1211
Container-title:Epilepsy Research
language:en
Short-container-title:Epilepsy Research

Author:

Walton Nancy Y.,Gunawan Sonny,Treiman David M.

Publisher

Elsevier BV

Subject

Clinical Neurology,Neurology

Reference24 articles.

1. The synthesis of novel GABA uptake inhibitors: 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate;Andersen;J. Med. Chem.,1993

2. (R)-N-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]nipecotic acid binds with high affinity to the brain gamma-aminobutyric acid uptake carrier;Braestrup;J. Neurochem.,1990

3. Protection against dendrotoxin-induced seizures in mice by anticonvulsant drugs;Coleman;Brain Res.,1992

4. Anticonvulsant activity of GABA uptake inhibitors and their prodrugs following central or systemic administration;Croucher;Eur. J. Pharmacol.,1983

5. The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats;Fink-Jensen;Eur. J. Pharmacol.,1992

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