Cell immortalization as a key, rate-limiting event in malignant transformation: approaches toward a molecular genetic analysis

Author:

Newbold Robert F.,Cuthbert Andrew P.,Themis Michael,Trott Debbie A.,Blair Andrea L.,Li Wei

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference25 articles.

1. Chemical carcinogenesis: Too many rodent carcinogens;Ames,1990

2. Exaggerated carcinogenicity of chemicals;Abelson;Science,1992

3. Induction of immortality is an early event in the malignant transformation of mammalian cells by carcinogens;Newbold;Nature,1982

4. Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene;Newbold;Nature,1983

5. Malignant transformation of mammalian cells in culture: delineation of stages and role of oncogene activation;Newbold,1985

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