Variability of physiologically based pharmacokinetic (PBPK) model parameters and their effects on PBPK model predictions in a risk assessment for perchloroethylene (PCE)-Reference-Cited by-同舟云学术

Variability of physiologically based pharmacokinetic (PBPK) model parameters and their effects on PBPK model predictions in a risk assessment for perchloroethylene (PCE)

Published:1993-05 Issue:1-2 Volume:68 Page:131-144
ISSN:0378-4274
Container-title:Toxicology Letters
language:en
Short-container-title:Toxicology Letters

Author:

Gearhart J.M.,Mahle D.A.,Greene R.J.,Seckel C.S.,Flemming C.D.,Fisher J.W.,Clewell H.J.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference16 articles.

1. Physiologically based pharmacokinetics and the risk assessment process for methylene chloride;Andersen;Toxicol. Appl. Pharmacol.,1987

2. Development of a physiologically based pharmacokinetic model for risk assessment with 1,4-dioxane;Reitz;Toxicol. Appl. Pharmacol.,1990

3. A physiologically based pharmacokinetic and pharmacodynamic model to describe the oral dosing of rats with ethyl acrylate and its implications for risk assessment;Frederick;Toxicol. Appl. Pharmacol.,1992

4. Precision and sensitivity of pharmacokinetic models for cancer risk assessment: tetrachloroethylene in mice, rats, and humans;Bois;Toxicol. Appl. Pharmacol.,1990

5. Evaluation of uncertainity in input parameters to pharmacokinetic models and the resulting uncertainity in output;Farrar;Toxicol. Lett.,1989

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