Pharmacokinetics, biochemical mechanism and mutation accumulation: a comprehensive model of chemical carcinogenesis

Author:

Conolly Rory B.,Reitz Richard H.,Clewell Harvey J.,Andersen Melvin E.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference27 articles.

1. Drug distribution in mammals;Bischoff,1966

2. Pharmacokinetics of PCBs;Matthews;Annu. Rev. Pharmacol. Toxicol.,1984

3. A physiological model for the inhalation pharmacokinetics of inhaled styrene in rats and humans;Ramsey;Toxicol. Appl. Pharmacol.,1984

4. Physiologically based pharmacokinetics and the risk assessment process for methylene chloride;Andersen;Toxicol. Appl. Pharmacol.,1987

5. Two-event models for carcinogenesis: incidence curves for childhood and adult tumors;Moolgavkar;Math. Biosci.,1979

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