Endosomal proteolysis of internalized proteins
Author:
Publisher
Wiley
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1016/0014-5793(96)00368-7/fullpdf
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1. Macrophage endosomes contain proteases which degrade endocytosed protein ligands.
2. Degradation of endocytosed insulin in rat liver is mediated by low-density vesicles
3. Fate of injected glucagon taken up by rat liver in vivo. Degradation of internalized ligand in the endosomal compartment
4. Degradation of glucagon in isolated liver endosomes. ATP-dependence and partial characterization of degradation products
5. Ligand-mediated internalization of glucagon receptors in intact rat liver.
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