Analysis of β-tubulin sequences reveals highly conserved, coordinated amino acid substitutions
Author:
Publisher
Wiley
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1016/0014-5793(90)80359-Q/fullpdf
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1. Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classes.
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3. In vivo coassembly of a divergent beta-tubulin subunit (c beta 6) into microtubules of different function.
4. In vivo microtubules are copolymers of available beta-tubulin isotypes: localization of each of six vertebrate beta-tubulin isotypes using polyclonal antibodies elicited by synthetic peptide antigens.
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