A novel property of a mitochondrial presequence
Author:
Publisher
Wiley
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1016/0014-5793(93)80164-P/fullpdf
Reference51 articles.
1. Effects of Synthetic Model Peptides Resembling the Extension Peptides of Mitochondrial Enzyme Precursors on Import of the Precursors into Mitochondria1
2. Mitochondrial targeting sequences may form amphiphilic helices.
3. A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers.
4. Amphiphilicity is essential for mitochondrial presequence function.
5. The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix.
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