Conversion of benzo[a]pyrene-3,6-quinone to quinol glucuronides with rat liver microsomes or purified nadph-cytochrome c reductase and UDP-glucuronosyltransferase
Author:
Publisher
Wiley
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1016/0014-5793(80)80359-0/fullpdf
Reference22 articles.
1. Enzymatic conjugation of benzo(a)pyrene oxides, phenols and dihydrodiols with UDP-glucuronic acid
2. Activation and induction of rat liver microsomal UDP-glucuronyltransferase with 3-hydroxybenzo(a)pyrene and N-hydroxy-2-naphthylamine as substrates
3. Functional heterogeneity of UDP-glucuronyltransferase in rat tissues
4. Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide
5. Metabolism of benzo(a)pyrene-3,6-quinone and 3-hydroxybenzo(a)pyrene in liver microsomes from 3-methylcholanthrene-treated rats
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1. UDP-glucuronosyltransferases 1A6 and 1A10 catalyze reduced menadione glucuronidation;Biochemical and Biophysical Research Communications;2008-06
2. Human Interindividual Variation in Lymphocyte UDP-Glucuronosyltransferases as a Determinant of In Vitro Benzo[a]pyrene Covalent Binding and Cytotoxicity;Toxicological Sciences;2004-01-21
3. DT-Diaphorase Affects the Mutagenic Activity of Pyrene 1,6-Quinone in Chinese Hamster Epithelial Liver (CHEL) Cells;Alternatives to Laboratory Animals;1996-08
4. Glucuronosyltransferase;Enzyme Handbook 12;1996
5. Induction of chromosomal aberrations and spindle disturbances in Chinese hamster epithelial liver cells in culture by pyrene and benzo[a]pyrene quinones;Mutagenesis;1995
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