We need to talk about the analytical performance of our laboratory developed clinical LC-MS/MS tests, and start separating the wheat from the chaff

Author:

Dirks Niek F.ORCID,Ackermans Mariëtte T,Martens FransORCID,Cobbaert Christa M.ORCID,de Jonge Robert,Heijboer Annemieke C.ORCID

Publisher

Elsevier BV

Subject

Biochemistry, medical,Clinical Biochemistry,Biochemistry,General Medicine

Reference17 articles.

1. Draft Guidance for Industry, Food and Drug Administration Staff, and Clinical Laboratories. FDA Notification and Medical Device Reporting for Laboratory Developed Tests (LDTs), 2014.

2. REGULATION (EU) 2017/746 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 5 April 2017 on in vitro diagnostic medical devices and repealing Directive 98/79/EC and Commission Decision 2010/227/EU, Official Journal of the European Union, 2017.

3. Defining analytical performance specifications: Consensus Statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine;Sandberg;Clin. Chem. Lab. Med.,2015

4. Practical guide for identifying unmet clinical needs for biomarkers;Monaghan;EJIFCC,2018

5. Setting clinical performance specifications to develop and evaluate biomarkers for clinical use;Lord;Ann. Clin. Biochem.,2019

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