Dihydrokaempferol attenuates CCl4-induced hepatic fibrosis by inhibiting PARP-1 to affect multiple downstream pathways and cytokines

Author:

Huang Hancheng,Wei Shuchun,Wu Xiaohan,Zhang Mengke,Zhou Benhong,Huang Debin,Dong Weiguo

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference38 articles.

1. Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins;Alemasova;Nucleic Acids Res.,2019

2. BMP-9 interferes with liver regeneration and promotes liver fibrosis;Breitkopf-Heinlein;Gut.,2017

3. 5-O-Demethylnobiletin alleviates CCl(4)-induced acute liver injury by equilibrating ROS-mediated apoptosis and autophagy induction;Chang;Int. J. Mol. Sci.,2021

4. Kaempferol alleviates acute alcoholic liver injury in mice by regulating intestinal tight junction proteins and butyrate receptors and transporters;Chen;Toxicology.,2020

5. Use of PYMOL as a communications tool for molecular science;DeLano;Abstr. Pap. Am. Chem. Soc.,2004

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