The effect of dose on 2,3,7,8-TCDD tissue distribution, metabolism and elimination in CYP1A2 (-/-) knockout and C57BL/6N parental strains of mice

Author:

Hakk Heldur,Diliberto Janet J.,Birnbaum Linda S.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference43 articles.

1. PCDD metabolites formed by mouse liver microsomes;Aozosa;Organohalog. Cmpd.,1995

2. Role of Ah receptor in the induction of cytochrome P450 1A1 and 1A2 enzymes in response to TCDD exposure;Batra;Toxicologist,1994

3. Distribution and excretion of 2,3,7,8-tetrachlorodibenzo-p-dioxin in congenic strains of mice which differ at the Ah locus;Birnbaum;Drug Metab. Dispos.,1986

4. Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-mediated hepatotoxicity;Boverhof;Toxicol. Sci.,2005

5. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein–dye binding;Bradford;Anal. Biochem.,1976

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