In utero bisphenol AF exposure causes fetal Leydig cell dysfunction and induces multinucleated gonocytes by generating oxidative stress and reducing the SIRT1/PGC1α signals

Author:

Tian Fuhong,Li Qiyao,Shi Lei,Li Jingjing,Shi Mengna,Zhu Yang,Li Huitao,Ge Ren-shan

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference57 articles.

1. Oxidative stress activates AMPK in cultured cells primarily by increasing cellular AMP and/or ADP;Auciello;FEBS Lett.,2014

2. Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate;Barlow;Toxicol. Sci.,2003

3. Aging and Luteinizing Hormone Effects on Reactive Oxygen Species Production and DNA Damage in Rat Leydig Cells;Beattie,2013

4. PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure;Canto;Curr. Opin. Lipidol.,2009

5. Leydig cells: from stem cells to aging;Chen;Mol. Cell. Endocrinol.,2009

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