Extension of a PBPK model for ethylene glycol and glycolic acid to include the competitive formation and clearance of metabolites associated with kidney toxicity in rats and humans-Reference-Cited by-同舟云学术

Extension of a PBPK model for ethylene glycol and glycolic acid to include the competitive formation and clearance of metabolites associated with kidney toxicity in rats and humans

Published:2011-02 Issue:3 Volume:250 Page:229-244
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Corley R.A.,Saghir S.A.,Bartels M.J.,Hansen S.C.,Creim J.,McMartin K.E.,Snellings W.M.

Funder

Ethylene Glycol Panel, American Chemistry Council

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

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5. Incorporation of therapeutic interventions in physiologically based pharmacokinetic modeling of human clinical case reports of accidental or intentional overdosing with ethylene glycol;Corley;Toxicol. Sci.,2005

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