Protective effect of sestrin2 against iron overload and ferroptosis-induced liver injury

Author:

Park Su Jung,Cho Sam Seok,Kim Kyu Min,Yang Ji Hye,Kim Jae Hoon,Jeong Eun Hee,Yang Jin Won,Han Chang Yeob,Ku Sae Kwang,Cho Il Je,Ki Sung Hwan

Funder

National Research Foundation of Korea

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference34 articles.

1. Review on iron and its importance for human health;Abbaspour;J. Res. Med. Sci.,2014

2. Dysregulation of iron and copper homeostasis in nonalcoholic fatty liver;Aigner;World J. Hepatol.,2015

3. Mechanisms of iron loading and toxicity;Anderson;Am. J. Hematol.,2007

4. Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage;Bae;Cell Metab.,2013

5. Regulators of Iron homeostasis: new players in metabolism, cell death, and disease;Bogdan;Trends Biochem. Sci.,2016

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