Prodigiosin inhibits gp91phox and iNOS expression to protect mice against the oxidative/nitrosative brain injury induced by hypoxia

Prodigiosin inhibits gp91phox and iNOS expression to protect mice against the oxidative/nitrosative brain injury induced by hypoxia–ischemia

Published:2011-11 Issue:1 Volume:257 Page:137-147
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Chang Chia-Che,Wang Yea-Hwey,Chern Chang-Ming,Liou Kuo-Tong,Hou Yu-Chang,Peng Yu-Ta,Shen Yuh-Chiang

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference35 articles.

1. IL-1beta regulates blood–brain barrier permeability via reactivation of the hypoxia-angiogenesis program;Argaw;J. Immunol.,2006

2. Arachidonate and NADPH oxidase synergise with iNOS to induce death in macrophages: mechanisms of inflammatory degeneration;Borutaite;Pharmacol. Rep.,2006

3. Development of natural anti-tumor drugs by microorganisms;Chang;J. Biosci. Bioeng.,2011

4. Prodeath or prosurvival: two facets of hypoxia inducible factor-1 in perinatal brain injury;Chen;Exp. Neurol.,2009

5. Andrographolide inhibits PI3K/AKT-dependent NOX2 and iNOS expression protecting mice against hypoxia/ischemia-induced oxidative brain injury;Chern;Planta Med.,2011

Cited by 39 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Prodigiosin as an Antibiofilm Agent against the Bacterial Biofilm-Associated Infection of Pseudomonas aeruginosa;Pathogens;2024-02-05

2. PtrA regulates prodigiosin synthesis and biological functions in Serratia marcescens FZSF02;Frontiers in Microbiology;2023-09-15

3. Neuroprotective efficacy of the bacterial metabolite, prodigiosin, against aluminium chloride‐induced neurochemical alternations associated with Alzheimer's disease murine model: Involvement of Nrf2/ HO ‐1/ NF‐κB signaling;Environmental Toxicology;2022-11-29

4. Concerted regulation of OPG/RANKL/ NF‑κB/MMP-13 trajectories contribute to ameliorative capability of prodigiosin and/or low dose γ-radiation against adjuvant- induced arthritis in rats;International Immunopharmacology;2022-10

5. Therapeutic antischizophrenic activity of prodigiosin and selenium co-supplementation against amphetamine hydrochloride-induced behavioural changes and oxidative, inflammatory, and apoptotic challenges in rats;Environmental Science and Pollution Research;2022-09-01