Neuromuscular paralysis by the basic phospholipase A 2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage

Author:

Cavalcante Walter L.G.,Noronha-Matos José B.,Timóteo Maria A.,Fontes Marcos R.M.,Gallacci Márcia,Correia-de-Sá PauloORCID

Funder

Fundação de Amparo a Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação para a Ciência e a Tecnologia

University of Porto/Santander Totta

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference51 articles.

1. Crotoxin from Crotalus durissus terrificus is able to down-modulate the acute intestinal inflammation in mice;Almeida;PLoS One,2015

2. Intracellular movements of fluorescently labeled synaptic vesicles in frog motor nerve terminals during nerve stimulation;Betz;Neuron,1992

3. Postsynaptic effects of crotoxin and of its isolated subunits;Bon;Eur. J. Biochem.,1979

4. Pharmacology of crystalline crotoxin. II. Neuromuscular blocking action;Brazil;Mem. Inst. Butantan,1966

5. Action of crotoxin and crotactin from the venom of Crotalus durissus terrificus (South American rattlesnake) on the frog neuromuscular junction;Brazil;J. Physiol.,1971

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