Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensitivity occurrence in humans-Reference-Cited by-同舟云学术

Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensitivity occurrence in humans

Published:2013-08 Issue:1 Volume:271 Page:30-40
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Tamura Akitoshi,Miyawaki Izuru,Yamada Toru,Kimura Juki,Funabashi Hitoshi

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference39 articles.

1. How do we avoid developing allergy: modifications of the TH2 response from a B-cell perspective;Aalberse;J. Allergy Clin. Immunol.,2004

2. Differential gene expression responses distinguish contact and respiratory sensitizers and nonsensitizing irritants in the local lymph node assay;Adenuga;Toxicol. Sci.,2012

3. Task force report: future research needs for the prevention and management of immune-mediated drug hypersensitivity reactions;Adkinson;J. Allergy Clin. Immunol.,2002

4. Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules;Aiba;Eur. J. Immunol.,1997

5. The cytokine-dependent MUTZ-3 cell line as an in vitro model for the screening of contact sensitizers;Azam;Toxicol. Appl. Pharmacol.,2006

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Chitosan based nanocarriers as a promising tool in treatment and management of inflammatory diseases;Carbohydrate Polymer Technologies and Applications;2024-06

2. Alphataxin, an Orally Available Small Molecule, Decreases LDL Levels in Mice as a Surrogate for the LDL-Lowering Activity of Alpha-1 Antitrypsin in Humans;Frontiers in Pharmacology;2021-06-09

3. Drugs frequently involved in inducing hypersensitivity reactions;Drug and Chemical Toxicology;2020-04-05