Paeoniflorin alleviated muscle atrophy in cancer cachexia through inhibiting TLR4/NF-κB signaling and activating AKT/mTOR signaling

Author:

Zhu Zixia,Li Cong,Gu Xiaofan,Wang Xiaoting,Zhang Gang,Fan Meng,Zhao Yun,Liu Xuan,Zhang Xiongwen

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference35 articles.

1. Cancer cachexia: understanding the molecular basis;Argilés;Nat. Rev. Cancer,2014

2. Cancer-associated cachexia;Baracos;Nat. Rev. Dis. Primers,2018

3. Matrine improves skeletal muscle atrophy by inhibiting E3 ubiquitin ligases and activating the Akt/mTOR/FoxO3α signaling pathway in C2C12 myotubes and mice;Chen;Oncol. Rep.,2019

4. Saikosaponin D alleviates cancer cachexia by directly inhibiting STAT3;Chen;Phytother. Res.,2023

5. Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia;Chiappalupi;J. Cachexia. Sarcopenia Muscle,2020

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