Comparing the cardiovascular therapeutic indices of glycopyrronium and tiotropium in an integrated rat pharmacokinetic, pharmacodynamic and safety model-Reference-Cited by-同舟云学术

Comparing the cardiovascular therapeutic indices of glycopyrronium and tiotropium in an integrated rat pharmacokinetic, pharmacodynamic and safety model

Published:2015-08 Issue:1 Volume:287 Page:9-16
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Trifilieff Alexandre,Ethell Brian T.,Sykes David A.,Watson Kenny J.,Collingwood Steve,Charlton Steven J.,Kent Toby C.

Funder

Novartis Pharma AG

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference31 articles.

1. Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder;Abrams;Br. J. Pharmacol.,2006

2. Preoperative glycopyrrolate: oral, intramuscular, or intravenous administration;Bernstein;J. Clin. Anesth.,1996

3. Goodman and Gilman's The Pharmacological Basis of Therapeutics;Brown,2001

4. Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease;Celli;Am. J. Respir. Crit. Care Med.,2009

5. Cardiovascular safety of tiotropium in patients with COPD;Celli;Chest,2010

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