Berberine induced modulation of PHLPP2-Akt-MST1 kinase signaling is coupled with mitochondrial impairment and hepatoma cell death

Author:

Saxena Sugandh,Shukla Shatrunajay,Kakkar PoonamORCID

Funder

Council of Scientific & Industrial Research

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference54 articles.

1. Antihyperglycemic and antihyperlipidemic effects of fruit aqueous extract of Berberis integerrima Bge. in streptozotocin-induced diabetic rats;Ashraf;Iran. J. Pharm. Res.,2014

2. Hepatocellular carcinoma epidemiology;Bosetti;Best Pract. Res. Clin. Gastroenterol.,2014

3. Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis;Brentnall;BMC Cell Biol.,2013

4. PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms;Brognard;Mol. Cell,2007

5. Flowcytometric analysis of the effect of berberine on the expression of glucocorticoid receptors in human hepatoma HepG2 cells;Chi;Life Sci.,1994

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