Development of an updated PBPK model for trichloroethylene and metabolites in mice, and its application to discern the role of oxidative metabolism in TCE-induced hepatomegaly
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Cited by 23 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Quantitative Characterization of Population-Wide Tissue- and Metabolite-Specific Variability in Perchloroethylene Toxicokinetics in Male Mice;Toxicological Sciences;2021-05-14
2. Differential toxicity of water versus gavage exposure to trichloroethylene in rats;Environmental Toxicology and Pharmacology;2019-05
3. Population-based dose–response analysis of liver transcriptional response to trichloroethylene in mouse;Mammalian Genome;2018-01-20
4. Evaluation and calibration of high-throughput predictions of chemical distribution to tissues;Journal of Pharmacokinetics and Pharmacodynamics;2017-10-14
5. Bayesian evaluation of a physiologically-based pharmacokinetic (PBPK) model of long-term kinetics of metal nanoparticles in rats;Regulatory Toxicology and Pharmacology;2015-10
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