Insufficient secretion of pancreatic FGF21 is the toxicological mechanism and therapeutic target of asparaginase-associated pancreatitis

Author:

He Jiang,Chen Yajing,Zhong Wen,Jun Lu,Chen Dong,Cheng Hui,Mei Wang

Publisher

Elsevier BV

Reference28 articles.

1. Role of activating transcription factor 4 in the hepatic response to amino acid depletion by asparaginase;Al-Baghdadi;Sci. Rep.,2017

2. Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune and Autophagy Processes to Restrict Zika Virus;Badu,2023

3. GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase;Bunpo;J. Biol. Chem.,2009

4. FGF21 is an exocrine pancreas Secretagogue;Coate;Cell Metab.,2017

5. Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation;De Sousa-Coelho;Biochem. J.,2012

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