DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A2A receptor-Reference-Cited by-同舟云学术

DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A2A receptor

Published:2019-04 Issue: Volume:368 Page:63-71
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Silva Rangel L.,Silveira Gabriela T.,Wanderlei Carlos W.,Cecilio Nerry T.,Maganin Alexandre G.M.,Franchin Marcelo,Marques Lucas M.M.,Lopes Norberto P.,Crippa José A.,Guimarães Francisco S.,Alves-Filho José C.F.,Cunha Fernando Q.,Cunha Thiago M.^ORCID

Funder

São Paulo Research Foundation

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference46 articles.

1. New cannabidiol derivatives: synthesis, binding to cannabinoid receptor, and evaluation of their antiinflammatory activity;Ben-Shabat;J. Med. Chem.,2006

2. Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress;Booz;Free Radic. Biol. Med.,2011

3. Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling;Börner;J. Biol. Chem.,2009

4. Fluorinated cannabidiol derivatives: enhancement of activity in mice models predictive of anxiolytic, antidepressant and antipsychotic effects;Breuer;PLoS One,2016

5. Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay;Bruggisser;Planta Med.,2002

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