DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A2A receptor

Author:

Silva Rangel L.,Silveira Gabriela T.,Wanderlei Carlos W.,Cecilio Nerry T.,Maganin Alexandre G.M.,Franchin Marcelo,Marques Lucas M.M.,Lopes Norberto P.,Crippa José A.,Guimarães Francisco S.,Alves-Filho José C.F.,Cunha Fernando Q.,Cunha Thiago M.ORCID

Funder

São Paulo Research Foundation

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference46 articles.

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3. Cannabinoid receptor type 1- and 2-mediated increase in cyclic AMP inhibits T cell receptor-triggered signaling;Börner;J. Biol. Chem.,2009

4. Fluorinated cannabidiol derivatives: enhancement of activity in mice models predictive of anxiolytic, antidepressant and antipsychotic effects;Breuer;PLoS One,2016

5. Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay;Bruggisser;Planta Med.,2002

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