Smarca2 genetic ablation is phenotypically benign in a safety assessment of tamoxifen-inducible conditional knockout rats-Reference-Cited by-同舟云学术

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Smarca2 genetic ablation is phenotypically benign in a safety assessment of tamoxifen-inducible conditional knockout rats

Published:2023-09 Issue: Volume:475 Page:116627
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Maher Jonathan,Stagg Nicola,Cain Gary,Andaya Roxanne,Katavolos Paula,Gallardo-Chang Fermin,Pham Anna,Ye Xiaofen,Januario Tom,Alcantar Tuija,Caothien Roger,Roose-Girma Merone,Zhang Donglu,Li Ruina,Chen Shu,Yauch Robert L.

Funder

Genentech

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference41 articles.

1. CRISPR off-target analysis in genetically engineered rats and mice;Anderson;Nat. Methods,2018

2. A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes;Bultman;Mol. Cell,2000

3. Mammalian SWI/SNF chromatin remodeling complexes: emerging mechanisms and therapeutic strategies;Centore;Trends Genet.,2020

4. Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung;Concepcion;Cancer Disc.,2022

5. Optimization of tamoxifen-induced Cre activity and its effect on immune cell populations;Donocoff;Sci. Rep.,2020

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1. Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs;Communications Medicine;2024-05-16

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