Verification of the seizure liability of compounds based on their in vitro functional activity in cultured rat cortical neurons and co-cultured human iPSC-derived neurons with astrocytes and in vivo extrapolation to cerebrospinal fluid concentration-Reference-Cited by-同舟云学术

Verification of the seizure liability of compounds based on their in vitro functional activity in cultured rat cortical neurons and co-cultured human iPSC-derived neurons with astrocytes and in vivo extrapolation to cerebrospinal fluid concentration

Published:2023-10 Issue: Volume:476 Page:116675
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Ishibashi Y.,Nagafuku N.,Kinoshita K.,Okamura A.,Shirakawa T.,Suzuki I.

Funder

Japan Agency for Medical Research and Development

Astellas Pharma

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

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