Mercury intoxication disrupts tonic signaling in B cells, and may promote autoimmunity due to abnormal phosphorylation of STIM-1 and other autoimmunity risk associated phosphoproteins involved in BCR signaling-Reference-Cited by-同舟云学术

Mercury intoxication disrupts tonic signaling in B cells, and may promote autoimmunity due to abnormal phosphorylation of STIM-1 and other autoimmunity risk associated phosphoproteins involved in BCR signaling

Published:2023-09 Issue: Volume:474 Page:116607
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Carruthers N.J.,Guo C.,Gill R.,Stemmer P.M.,Rosenspire A.J.

Funder

National Institutes of Health Office of the Director

National Cancer Institute

National Institute of Environmental Health Sciences

East Carolina University

National Institutes of Health

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

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5. BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling;Bernal-Quiros;PLoS One,2013

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1. Naturally occurring autoimmune disease in (NZB × NZW) F1 mice is correlated with suppression of MZ B-cell development due to aberrant B-cell receptor (BCR) signaling, which is exacerbated by exposure to inorganic mercury;Toxicological Sciences;2023-11-11