Network pharmacology and molecular docking analysis on molecular targets: Mechanisms of baicalin and baicalein against hyperuricemic nephropathy-Reference-Cited by-同舟云学术

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Network pharmacology and molecular docking analysis on molecular targets: Mechanisms of baicalin and baicalein against hyperuricemic nephropathy

Published:2021-08 Issue: Volume:424 Page:115594
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Xiang Huilong,Lei Huan,Liu Ziyuan,Liu Yongjie,Li Yang,Qiu Yinsheng,Xu Lingyun

Funder

National Natural Science Foundation of China

Hubei Key Laboratory of Animal Nutrition and Feed Science

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference68 articles.

1. Prophylactic effect of baicalein against renal dysfunction in type 2 diabetic rats;Ahad;Biochimie.,2014

2. Baicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form;Akao;J. Pharm. Pharmacol.,2000

3. Mechanisms of inflammation in gout;Busso;Arthritis Res. Ther.,2010

4. Soluble uric acid increases PDZK1 and ABCG2 expression in human intestinal cell lines via the TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway;Chen;Arthritis Res. Ther.,2018

5. Baicalein alleviates hyperuricemia by promoting uric acid excretion and inhibiting xanthine oxidase;Chen;Phytomedicine.,2021

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2. Simiao pills alleviates renal injury associated with hyperuricemia: A multi-omics analysis;Journal of Ethnopharmacology;2024-10

3. Baicalein suppresses Coxsackievirus B3 replication by inhibiting caspase-1 and viral protease 2A;Virologica Sinica;2024-08

4. Synthesis, characterization, and mechanistic insights into the enhanced anti-inflammatory activity of baicalin butyl ester via the PI3K-AKT pathway;Frontiers in Pharmacology;2024-07-22

5. Preparing a novel baicalin-loaded microemulsion-based gel for transdermal delivery and testing its anti-gout effect;Saudi Pharmaceutical Journal;2024-06

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