Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients

Author:

Al Dubayee Mohammed,Alshahrani Awad,Almalk Malak,Hakami Alanoud,Homoud Bareen,Alzneidi Nowar,Aldhalaan Jumana,Aljbli Ghaidaa,Nasr Amre,Farahat Ahmed I.,Aljada Ahmad

Funder

King Abdulaziz City for Science and Technology

Publisher

Elsevier BV

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference78 articles.

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3. Wang JC, Bennett M. Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence. Circulation research. 2012;111(2): 245–259. https://doi.org/10.1161/CIRCRESAHA.111.261388:

4. Ressler S, Bartkova J, Niederegger H, et al. p16INK4A is a robust in vivo biomarker of cellular aging in human skin. Aging Cell. 2006;5(5): 379–389.ACE231 [pii] https://doi.org/10.1111/j.1474-9726.2006.00231.x:

5. Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints;Chen;Ann N Y Acad Sci,2000

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