Polygenic Background Modifies Risk of Coronary Artery Disease Among Individuals With Heterozygous Familial Hypercholesterolemia
Author:
Funder
National Human Genome Research Institute
Eli and Edythe L Broad Institute of Harvard and MIT
Publisher
Elsevier BV
Reference38 articles.
1. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society;Nordestgaard;Eur Heart J,2013
2. Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217;Benn;Eur Heart J,2016
3. Diagnostic yield and clinical utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia;Khera;J Am Coll Cardiol,2016
4. Association of the interaction between familial hypercholesterolemia variants and adherence to a healthy lifestyle with risk of coronary artery disease;Fahed;JAMA Netw Open,2022
5. SAFEHEART risk-equation and cholesterol-year-score are powerful predictors of cardiovascular events in French patients with familial hypercholesterolemia;Gallo;Atherosclerosis,2020
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