Muscarinic drug shows efficacy in schizophrenia but much is left to be discovered

Author:

Cipriani Andrea,Agunbiade Adeola,Salanti Georgia

Publisher

Elsevier BV

Subject

General Medicine

Reference14 articles.

1. Schizophrenia;Jauhar;Lancet,2022

2. The future of psychopharmacology: a critical appraisal of ongoing phase 2/3 trials, and of some current trends aiming to de-risk trial programmes of novel agents;Correll;World Psych,2023

3. Muscarinic acetylcholine receptor agonists 537 as novel treatments for schizophrenia;Paul;Am J Psychiatry,2022

4. Evidence of trospium's ability to mitigate cholinergic 549 adverse events related to xanomeline: phase 1 study results;Breier;Psychopharmacology,2023

5. Efficacy and safety of the muscarinic receptor agonist KarXT (xanomeline–trospium) in schizophrenia (EMERGENT-2) in the USA: results from a randomised, double-blind, placebo-controlled, flexible-dose phase 3 trial;Kaul;Lancet,2023

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