Efficacy and safety of the muscarinic receptor agonist KarXT (xanomeline–trospium) in schizophrenia (EMERGENT-2) in the USA: results from a randomised, double-blind, placebo-controlled, flexible-dose phase 3 trial-Reference-Cited by-同舟云学术

Efficacy and safety of the muscarinic receptor agonist KarXT (xanomeline–trospium) in schizophrenia (EMERGENT-2) in the USA: results from a randomised, double-blind, placebo-controlled, flexible-dose phase 3 trial

Published:2024-01 Issue:10422 Volume:403 Page:160-170
ISSN:0140-6736
Container-title:The Lancet
language:en
Short-container-title:The Lancet

Author:

Kaul Inder,Sawchak Sharon,Correll Christoph U,Kakar Rishi,Breier Alan,Zhu Haiyuan,Miller Andrew C,Paul Steven M,Brannan Stephen K

Publisher

Elsevier BV

Subject

General Medicine

Reference38 articles.

1. Schizophrenia;Marder;N Engl J Med,2019

2. Schizophrenia;Jauhar;Lancet,2022

3. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019;Lancet,2020

4. Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019;Lancet Psychiatry,2022

5. The lifetime risk of suicide in schizophrenia: a reexamination;Palmer;Arch Gen Psychiatry,2005

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