Dietary supplements of mixtures of indispensable amino acids lacking threonine, phenylalanine or histidine increase the activity of hepatic threonine dehydrogenase, phenylalanine hydroxylase or histidase, respectively, and prevent growth depressions in chicks caused by dietary excesses of threonine, phenylalanine, or histidine☆

Author:

Keene Julie C.,Austic Richard E.

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Nutrition and Dietetics,Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference64 articles.

1. Harper, A.E., Benevenga, N.J., and Wohlhueter, R.M, Effects of ingestion of disproportionate amounts of amino acids, Physiol Rev 50, 428–558 (1970).

2. Benevenga, N.J. and Harper, A.E, Alleviation of methionine and homocystine toxicity in the rat, J Nutr 93, 44–52 (1967).

3. Ip, C.C.Y. and Harper, A.E, Effects of dietary protein content and glucagon administration on tyrosine metabolism and tyrosine toxicity in the rat, J Nutr 103, 1594–1607 (1973).

4. Harper, A.E., Becker, R.V., and Stucki, W.P, Some effects of excessive intakes of indispensable amino acids, Proc Soc Exp Biol Med 121, 695–699 (1966).

5. Muramatsu, K., Takei, M., and Nakamura, K, Effect of dietary protein on tyrosine toxicity in the rat, J Nutr 105, 439–446 (1975).

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