Could manipulation of the binding affinity of haemoglobin for oxygen be used clinically to sensitize tumours to radiation?

Author:

Hirst David G.,Wood Pauline J.

Publisher

Elsevier BV

Subject

Radiology, Nuclear Medicine and imaging,Oncology,Hematology

Reference21 articles.

1. Determination of the oxyhaemoglobin dissociation curves for mouse and rat blood;Gray;J. Physiol.,1964

2. Utilization of oxygen by transplanted tumours in vivo;Gullino;Cancer Res.,1967

3. Anaemia: a problem or an opportunity in radiotherapy?;Hirst;Int. J. Radiat. Oncol. Biol. Phys.,1986

4. Workshop report. Tumour hypoxia: implications for therapy;Hirst,1989

5. Hirst, D.G. Tumour radiosensitization by clofibrate and its analogues: possible mechanisms. Adv. Exper. Med. Biol. (in press).

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