Folates and antifolates in the treatment of cancer; role of folic acid supplementation on efficacy of folate and non-folate drugs

Author:

Peters G.J.,Hooijberg J.H.,Kaspers G.J.L.,Jansen G.

Publisher

Elsevier BV

Subject

Food Science,Biotechnology

Reference62 articles.

1. Augmentation of the therapeutic activity of lometrexol [(6R-)5,10-dideazatetrahydrofolate] by oral folic acid;Alati;Cancer Research,1996

2. Loss of folic acid exporter function with markedly augmented folate accumulation in lipophilic antifolate-resistant mammalian cells;Assaraf;Journal of Biological Chemistry,1997

3. Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells;Assaraf;Journal Biological Chemistry,2003

4. Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates;Backus;International Journal Cancer,2000

5. Metabolic turnover of methotrexate polyglutamates in lysosomes derived from S180 cells;Barrueco;Journal of Biological Chemistry,1992

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3. Medicines associated with folate–homocysteine–methionine pathway disruption;Archives of Toxicology;2018-11-29

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