An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

Author:

Cordell Heather J.ORCID,Fryett James J.,Ueno KazukoORCID,Darlay RebeccaORCID,Aiba YoshihiroORCID,Hitomi YukiORCID,Kawashima Minae,Nishida Nao,Khor Seik-SoonORCID,Gervais OlivierORCID,Kawai YosukeORCID,Nagasaki MasaoORCID,Tokunaga Katsushi,Tang Ruqi,Shi Yongyong,Li Zhiqiang,Juran Brian D.,Atkinson Elizabeth J.,Gerussi AlessioORCID,Carbone Marco,Asselta RosannaORCID,Cheung Angela,de Andrade Mariza,Baras Aris,Horowitz JulieORCID,Ferreira Manuel A.R.,Sun DylanORCID,Jones David E.,Flack StevenORCID,Spicer Ann,Mulcahy Victoria L.ORCID,Byan Jinyoung,Han Younghun,Sandford Richard N.ORCID,Lazaridis Konstantinos N.ORCID,Amos Christopher I.,Hirschfield Gideon M.ORCID,Seldin Michael F.,Invernizzi PietroORCID,Siminovitch Katherine A.,Ma Xiong,Nakamura Minoru,Mells George F.ORCID,Siminovitch Katherine A.,Hirschfield Gideon M.,Mason Andrew,Vincent Catherine,Xie Gang,Zhang Jinyi,Tang Ruqi,Ma Xiong,Li Zhiqiang,Shi Yongyong,Affronti Andrea,Almasio Piero L.,Alvaro Domenico,Andreone Pietro,Andriulli Angelo,Azzaroli Francesco,Battezzati Pier Maria,Benedetti Antonio,Bragazzi MariaConsiglia,Brunetto Maurizia,Bruno Savino,Calvaruso Vincenza,Cardinale Vincenzo,Casella Giovanni,Cazzagon Nora,Ciaccio Antonio,Coco Barbara,Colli Agostino,Colloredo Guido,Colombo Massimo,Colombo Silvia,Cristoferi Laura,Cursaro Carmela,Crocè Lory Saveria,Crosignani Andrea,D’Amato Daphne,Donato Francesca,Elia Gianfranco,Fabris Luca,Fagiuoli Stefano,Ferrari Carlo,Floreani Annarosa,Galli Andrea,Giannini Edoardo,Grattagliano Ignazio,Lampertico Pietro,Lleo Ana,Malinverno Federica,Mancuso Clara,Marra Fabio,Marzioni Marco,Massironi Sara,Mattalia Alberto,Miele Luca,Milani Chiara,Morini Lorenzo,Morisco Filomena,Muratori Luigi,Muratori Paolo,Niro Grazia A.,O’Donnell Sarah,Picciotto Antonio,Portincasa Piero,Rigamonti Cristina,Ronca Vincenzo,Rosina Floriano,Spinzi Giancarlo,Strazzabosco Mario,Tarocchi Mirko,Tiribelli Claudio,Toniutto Pierluigi,Valenti Luca,Vinci Maria,Zuin Massimo,Nakamura Hitomi,Abiru Seigo,Nagaoka Shinya,Komori Atsumasa,Yatsuhashi Hiroshi,Ishibashi Hiromi,Ito Masahiro,Migita Kiyoshi,Ohira Hiromasa,Katsushima Shinji,Naganuma Atsushi,Sugi Kazuhiro,Komatsu Tatsuji,Mannami Tomohiko,Matsushita Kouki,Yoshizawa Kaname,Makita Fujio,Nikami Toshiki,Nishimura Hideo,Kouno Hiroshi,Kouno Hirotaka,Ota Hajime,Komura Takuya,Nakamura Yoko,Shimada Masaaki,Hirashima Noboru,Komeda Toshiki,Ario Keisuke,Nakamuta Makoto,Yamashita Tsutomu,Furuta Kiyoshi,Kikuchi Masahiro,Naeshiro Noriaki,Takahashi Hironao,Mano Yutaka,Tsunematsu Seiji,Yabuuchi Iwao,Shimada Yusuke,Yamauchi Kazuhiko,Sugimoto Rie,Sakai Hironori,Mita Eiji,Koda Masaharu,Tsuruta Satoru,Kamitsukasa Hiroshi,Sato Takeaki,Masaki Naohiko,Kobata Tatsuro,Fukushima Nobuyoshi,Ohara Yukio,Muro Toyokichi,Takesaki Eiichi,Takaki Hitoshi,Yamamoto Tetsuo,Kato Michio,Nagaoki Yuko,Hayashi Shigeki,Ishida Jinya,Watanabe Yukio,Kobayashi Masakazu,Koga Michiaki,Saoshiro Takeo,Yagura Michiyasu,Hirata Keisuke,Tanaka Atsushu,Takikawa Hajime,Zeniya Mikio,Abe Masanori,Onji Morikazu,Kaneko Shuichi,Honda Masao,Arai Kuniaki,Arinaga-Hino Teruko,Hashimoto Etsuko,Taniai Makiko,Umemura Takeji,Joshita Satoru,Nakao Kazuhiko,Ichikawa Tatsuki,Shibata Hidetaka,Yamagiwa Satoshi,Seike Masataka,Honda Koichi,Sakisaka Shotaro,Takeyama Yasuaki,Harada Masaru,Senju Michio,Yokosuka Osamu,Kanda Tatsuo,Ueno Yoshiyuki,Kikuchi Kentaro,Ebinuma Hirotoshi,Himoto Takashi,Yasunami Michio,Murata Kazumoto,Mizokami Masashi,Kawata Kazuhito,Shimoda Shinji,Miyake Yasuhiro,Takaki Akinobu,Yamamoto Kazuhide,Hirano Katsuji,Ichida Takafumi,Ido Akio,Tsubouchi Hirohito,Chayama Kazuaki,Harada Kenichi,Nakanuma Yasuni,Maehara Yoshihiko,Taketomi Akinobu,Shirabe Ken,Soejima Yuji,Mori Akira,Yagi Shintaro,Uemoto Shinji,H Egawa,Tanaka Tomohiro,Yamashiki Noriyo,Tamura Sumito,Sugawara Yasuhiro,Kokudo Norihiro,Juran Brian D.,Atkinson Elizabeth J.,Cheung Angela,de Andrade Mariza,Lazaridis Konstantinos N.,Chalasani Naga,Luketic Vel,Odin Joseph,Chopra Kapil,Baras Aris,Horowitz Julie,Abecasis Goncalo,Cantor Michael,Coppola Giovanni,Economides Aris,Lotta Luca A.,Overton John D.,Reid Jeffrey G.,Shuldiner Alan,Beechert Christina,Forsythe Caitlin,Fuller Erin D.,Gu Zhenhua,Lattari Michael,Lopez Alexander,Overton John D.,Schleicher Thomas D.,Padilla Maria Sotiropoulos,Toledo Karina,Widom Louis,Wolf Sarah E.,Pradhan Manasi,Manoochehri Kia,Ulloa Ricardo H.,Bai Xiaodong,Balasubramanian Suganthi,Barnard Leland,Blumenfeld Andrew,Eom Gisu,Habegger Lukas,Hawes Alicia,Khalid Shareef,Reid Jeffrey G.,Maxwell Evan K.,Salerno William,Staples Jeffrey C.,Jones Marcus B.,Mitnaul Lyndon J.,Sturgess Richard,Healey Christopher,Yeoman Andrew,Gunasekera Anton VJ.,Kooner Paul,Kapur Kapil,Sathyanarayana V.,Kallis Yiannis,Subhani Javaid,Harvey Rory,McCorry Roger,Rooney Paul,Ramanaden David,Evans Richard,Mathialahan Thiriloganathan,Gasem Jaber,Shorrock Christopher,Bhalme Mahesh,Southern Paul,Tibble Jeremy A.,Gorard David A.,Jones Susan,Mells George,Mulcahy Victoria,Srivastava Brijesh,Foxton Matthew R.,Collins Carole E.,Elphick David,Karmo Mazn,Porras-Perez Francisco,Mendall Michael,Yapp Tom,Patel Minesh,Ede Roland,Sayer Joanne,Jupp James,Fisher Neil,Carter Martyn J.,Koss Konrad,Shah Jayshri,Piotrowicz Andrzej,Scott Glyn,Grimley Charles,Gooding Ian R.,Williams Simon,Tidbury Judith,Lim Guan,Cheent Kuldeep,Levi Sass,Mansour Dina,Beckley Matilda,Hollywood Coral,Wong Terry,Marley Richard,Ramage John,Gordon Harriet M.,Ridpath Jo,Ngatchu Theodore,Bob Grover Vijay Paul,Shidrawi Ray G.,Abouda George,Corless L.,Narain Mark,Rees Ian,Brown Ashley,Taylor-Robinson Simon,Wilkins Joy,Grellier Leonie,Banim Paul,Das Debasish,Heneghan Michael A.,Curtis Howard,Matthews Helen C.,Mohammed Faiyaz,Aldersley Mark,Srirajaskanthan Raj,Walker Giles,McNair Alistair,Sharif Amar,Sen Sambit,Bird George,Prince Martin I.,Prasad Geeta,Kitchen Paul,Barnardo Adrian,Oza Chirag,Sivaramakrishnan Nurani N.,Gupta Prakash,Shah Amir,Evans Chris DJ.,Saha Subrata,Pollock Katharine,Bramley Peter,Mukhopadhya Ashis,Barclay Stephen T.,McDonald Natasha,Bathgate Andrew J.,Palmer Kelvin,Dillon John F.,Rushbrook Simon M.,Przemioslo Robert,McDonald Chris,Millar Andrew,Tai Cheh,Mitchell Stephen,Metcalf Jane,Shaukat Syed,Ninkovic Mary,Shmueli Udi,Davis Andrew,Naqvi Asifabbas,Lee Tom JW.,Ryder Stephen,Collier Jane,Klass Howard,Cramp Matthew E.,Sharer Nichols,Aspinall Richard,Ghosh Deb,Douds Andrew C.,Booth Jonathan,Williams Earl,Hussaini Hyder,Christie John,Mann Steven,Thorburn Douglas,Marshall Aileen,Patanwala Imran,Ala Aftab,Maltby Julia,Matthew Ray,Corbett Chris,Vyas Sam,Singhal Saket,Gleeson Dermot,Misra Sharat,Butterworth Jeff,George Keith,Harding Tim,Douglass Andrew,Mitchison Harriet,Panter Simon,Shearman Jeremy,Bray Gary,Roberts Michael,Butcher Graham,Forton Daniel,Mahmood Zahid,Cowan Matthew,Das Debashis,Ch’ng Chin Lye,Rahman Mesbah,Whatley Gregory C.A.,Wesley Emma,Mandal Aditya,Jain Sanjiv,Pereira Stephen P.,Wright Mark,Trivedi Palak,Gordon Fiona H.,Unitt Esther,Palejwala Altaf,Austin Andrew,Vemala Vishwaraj,Grant Allister,Higham Andrew D.,Brind Alison,Mathew Ray,Cox Mark,Ramakrishnan Subramaniam,King Alistair,Whalley Simon,Fraser Jocelyn,Thomson S.J.,Bell Andrew,Wong Voi Shim,Kia Richard,Gee Ian,Keld Richard,Ransford Rupert,Gotto James,Millson Charles

Publisher

Elsevier BV

Subject

Hepatology

Reference35 articles.

1. Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants;Hirschfield;N Engl J Med,2009

2. Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis;Liu;Nat Genet,2010

3. Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis;Mells;Nat Genet,2011

4. Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population;Kawashima;Hum Mol Genet,2017

5. A genome-wide association study identifies six novel risk loci for primary biliary cholangitis;Qiu;Nat Commun,2017

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3