Pharmacological activation of aldehyde dehydrogenase 2 by Alda-1 reverses alcohol-induced hepatic steatosis and cell death in mice
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Hepatology
Reference29 articles.
1. Alcoholic liver disease: pathogenesis and new therapeutic targets;Gao;Gastroenterology,2011
2. Alcohol metabolism;Cederbaum;Clin Liver Dis,2012
3. Post-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications;Song;J Proteomics,2011
4. Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism;Mizoi;Alcohol Alcohol,1994
5. Aldehyde dehydrogenase 2 gene targeting mouse lacking enzyme activity shows high acetaldehyde level in blood, brain, and liver after ethanol gavages;Isse;Alcohol Clin Exp Res,2005
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