A phase 2a trial of 12-week interferon-free therapy with two direct-acting antivirals (ABT-450/r, ABT-072) and ribavirin in IL28B C/C patients with chronic hepatitis C genotype 1

Author:

Lawitz Eric,Poordad Fred,Kowdley Kris V.,Cohen Daniel E.,Podsadecki Thomas,Siggelkow Sara,Larsen Lois,Menon Rajeev,Koev Gennadiy,Tripathi Rakesh,Pilot-Matias Tami,Bernstein Barry

Publisher

Elsevier BV

Subject

Hepatology

Reference15 articles.

1. An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases;Ghany;Hepatology,2011

2. Clinical practice. Chronic hepatitis C infection;Rosen;New Engl J Med,2011

3. Pharmacokinetics and tolerability of the HCV protease inhibitor ABT-450 following single ascending doses in healthy adult volunteers with and without ritonavir;Menon;Global Antiviral J,2009

4. Initial antiviral activity of the HCV NS3 protease inhibitor ABT-450 when given with low dose ritonavir as 3-day monotherapy: preliminary results of study M11–602 in genotype 1 (GT1) HCV infected treatment-naïve subjects;Lawitz;Hepatology,2010

5. Genotypic and phenotypic characterization of NS3 variants selected in HCV-infected patients treated with ABT-450;Pilot-Matias;J Hepatol,2011

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