Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: Reversed by anti-TNF-α treatment
Author:
Funder
Ministerio de Ciencia e Innovación
Consellería Educación Generalitat Valenciana
European Regional Development Funds
Publisher
Elsevier BV
Subject
Hepatology
Reference33 articles.
1. Hepatic encephalopathy: effects of liver failure on brain function;Felipo;Nat Rev Neurosci,2013
2. Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis;Shawcross;J Hepatol,2004
3. IL-6 and IL-18 in blood may discriminate cirrhotic patients with and without minimal hepatic encephalopathy;Montoliu;J Clin Gastroenterol,2009
4. Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy;Felipo;Metab Brain Dis,2012
5. Minimal hepatic encephalopathy is associated with expansion and activation of CD4+CD28-, Th22 and Tfh and B lymphocytes;Mangas-Losada;Sci Rep,2017
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